Antidepressants Don’t Correct A Chemical Imbalance. How, Then, Do They Work? (Gift Article)

In my latest “Therapeutic Window” piece for the @nytimes.com, I discuss our current scientific understanding of how antidepressants work (Gift link but NYT requires an email sign up to read for free) www.nytimes.com/2026/10/27/s...

Millions Use Antidepressants. We Still Don’t Understand How They Work. Here’s how psychiatrists think about the most promising hypotheses, by @awaisaftab.bsky.social www.nytimes.com/2026/10/27/s... via @nytopinion.nytimes.com #MentalHealth

If you know what happened to my brain in 2024 you will know why I find this paragraph extremely funny www.nytimes.com/2026/10/27/s...

Explore this gift article from The New York Times. You can read it for free without a subscription. www.nytimes.com/2026/10/27/s...

Millions Use Antidepressants. We Still Don’t Understand How They Work. www.nytimes.com/2026/10/27/s...

Millions Use Antidepressants. We Still Don’t Understand How They Work. “A common theme among these hypotheses is that antidepressants alter the conditions under which people interact with the world and with their emotions.” www.nytimes.com/2026/10/27/s...

Millions Use Antidepressants. We Still Don’t Understand How They Work. www.nytimes.com/2026/10/27/s...

Explore this gift article from The New York Times. You can read it for free without a subscription. www.nytimes.com/2026/10/27/s...

www.nytimes.com/2026/10/27/s...

"We can think of the antidepressant here as a cast or a scaffold: It can come off once the work of healing and repair is complete. For people with isolated episodes of depression, this strategy works best." www.nytimes.com/2026/10/27/s...

Questions remain about how and if antidepressants "work." www.nytimes.com/2026/10/27/s...